Chicago Tri-Institutional Center for Chemical Methods and Library Development

The mission of the Chicago Tri-Institutional Center for Chemical Methods and Library Development (CTCMLD) is to address the fundamental challenges of modern high-throughput organic synthesis and to provide major advances that will significantly facilitate the development of small-molecule libraries for broad biological screening. The Chicago CMLD is jointly supported by the National Institute of General Medical Sciences (National Institutes of Health, P50 GM086145) and the Chicago Biomedical Consortium with support from the Searle Funds at the Chicago Community Trust (Lever Award). It bridges seven research groups from the three leading institutions in the Chicago area including University of Chicago, Northwestern University and University of Illinois at Chicago. The CTCMLD brings together exceedingly complementary expertise in organic synthesis, featuring a unique collaboration of five synthetic laboratories in three Chicago-area institutions. In addition, the Chicago CMLD provides an effective mechanism for the cross-disciplinary integration of the core synthetic effort. The Chicago CMLD brings a significant degree of collaboration within each project, as well as a considerable degree of integration between individual projects and the Core.

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