A researcher works inside the Engel Lab

Research and Scholarship

Research empowers discovery

Through their foundational research, UChicago scholars and students create knowledge in their fields and enable new areas for discovery.

Measuring the earliest light in the universe

Using the South Pole Telescope, UChicago scientists studied the cosmic microwave background to map the afterglow of the big bang.

Research improves our health

From advancing cancer immunotherapy to developing new treatments that target disease at the molecular level—our medical breakthroughs are impacting lives.

Inventing a pacemaker powered by light

UChicago researchers have created a featherlight, wireless implant that uses light to regulate heart or nerve activity, potentially replacing pacemakers.

Research tackles complex social problems

Breakthrough scholarship at UChicago has not only changed the way we think and view the world, but has benefitted society in fundamental ways.

Addressing complex problems in cities and schools

The UChicago Urban Labs use academic research to inform effective policy-making to help limit crime and improve education across the country.

Research drives technological advances

Discovery at UChicago is actively focused on solving problems, while developing and employing new techniques and innovative technology.

Advancing work toward a secure quantum internet

A 124-mile quantum network built in Chicago is one of the country’s first testbeds for quantum security technology.

From Idea to Industry

We turn groundbreaking research into new businesses. UChicago has helped entrepreneurs take big ideas—from new cancer treatments to green energy solutions—from the labs to the real world. Through the Polsky Center’s world-renowned New Venture Challenge, more than 370 startups have been launched, including Grubhub, Braintree/Venmo and Simple Mills.

Go inside our research labs

See how UChicago faculty and students are tackling some of the world’s most complex problems—from addressing climate change to preserving ancient objects.

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Feeding the world amid climate change
Chemist Chuan He’s lab developed a breakthrough method to increase rice and corn yields by 50%.
Overcoming learning loss
UChicago’s Education Lab found that intensive tutoring can double or triple student learning. 
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Predicting and preventing strokes
Neurosurgeon Isaam Awad’s lab is finding ways to prevent brain bleeds before they occur. 

By the numbers

101

Nobel laureates affiliated with UChicago

180K

Global network of UChicago alumni

10K

Papers published in 2024-25 school year

577

Patents filed by UChicago the past five years

Research that made history

Discover the fascinating stories and ‘eureka’ moments behind big, world-changing ideas at UChicago—and the people behind them.

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Redefined the field of economics
From Milton Friedman’s ideas on monetary policy to Gary Becker’s theory of human capital to Richard Thaler’s founding of the field of behavioral economics, UChicago scholars have transformed economic research. 
Unlocked the secrets of black holes
UChicago scientists have conducted groundbreaking research on black holes, beginning in 1930 when 19-year-old Subrahmanyan Chandrasekhar proposed the controversial idea that stars collapsed at the end of their lives—research that led to the discovery of black holes.
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Established the country’s first sleep lab
For the past century, UChicago have pioneered the study of sleep—from discovering REM sleep to unraveling sleep’s impact on our health.

Meet the Researchers

The doctor ushering in a new era of cancer research

A film archivist who keeps families’ memories alive

A scientist making plastics more recyclable

A ‘doctor for batteries’ tackling climate change

Our economic impact

UChicago faculty have played an influential role in shaping the U.S. economy, through their insights on financial policy or their work as economic advisors to presidents. Their breakthroughs in medicine have led to new cures, startups and industry partnerships—and their research in partnership with Argonne and Fermilab national laboratories have large-scale economic impact. Studies have shown that every $1 spent by the NIH generates $2.56 of economic activity.

Explore More UChicago Research

Big Brains podcast

A history of breakthrough research

UChicago Explainer Series